Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia.

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Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia

An infrequent (2-3%) B lymphocyte subpopulation was found in the normal human tonsil and lymph nodes that shows the phenotypic characteristics of B-chronic lymphocytic leukemia (B-CLL) (rosette formation with mouse erythrocytes, weak expression of membrane Ig, staining for HLA-DR, and OKT1 or Leu-1 detecting a T cell-associated p65 antigen). Preliminary evidence suggests that at least a subpopu...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1982

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.155.2.623